Ahmed Hosny

 

Highlights

Clinical Validation of Deep Learning Algorithms for Lung Cancer Radiotherapy Targeting ↗︎

A Hosny, DS Bitterman, CV Guthier, JM Qian, H Roberts, S Perni, A Saraf, LC Peng, I Pashtan, Z Ye, BH Kann, DE Kozono, D Christiani, PJ Catalano, HJWL Aerts & RH Mak

The Lancet Digital Health 2022

Deep Learning-based Computed Tomography Radiomics for Non-small Cell Lung Cancer Histopathologic Classification ↗︎

TL Chaunzwa, A Hosny, Y Xu, A Shafer, N Diao, M Lanuti, DC Christiani, RH Mak & HJWL Aerts

Nature Scientific Reports 2021

Artificial Intelligence for Global Health ↗︎

A Hosny & HJWL Aerts

Science 2019

Deep Learning Predicts Lung Cancer Treatment Response from Serial Medical Imaging ↗︎

Y Xu, A Hosny, R Zeleznik, C Parmar, T Coroller, I Franko, RH Mak & HJWL Aerts

Clinical Cancer Research 2019

Bioinspired Design of Flexible Armor Based on Chiton Scales ↗︎

M Connors*, T Yang*, A Hosny, Z Deng, F Yazdandoost, H Massaadi, D Eernisse, R Mirzaeifar, MN Dean, JC Weaver, C Ortiz & L Li

Nature Communications 2019

Artificial Intelligence in Radiology ↗︎

A Hosny, C Parmar, J Quackenbush, LZ Schwartz & HJWL Aerts

Nature Reviews Cancer 2018

Deep Learning for Lung Cancer Prognostication: A Retrospective Multi-Cohort Radiomics Study ↗︎

A Hosny, C Parmar, T Coroller, P Grossmann, R Zeleznik, A Kumar, J Bussink, RJ Gillies, RH Mak & HJWL Aerts

PLOS Medicine 2018

Pre-procedural Fit-testing of Transcatheter Aortic Valve Replacement (TAVR) Valves Using Parametric Modeling and 3D Printing ↗︎

A Hosny, J Dilley, T Kelil, M Mathur, M Dean, JC Weaver & B Ripley

Journal of Cardiovascular Computed Tomography 2018

From Improved Diagnostics to Presurgical Planning: High Resolution Functionally Graded Multi-material 3D Printing of Biomedical Tomographic Datasets ↗︎

A Hosny, S Keating, JD Dilley, B Ripley, T Kelil, S Pieper, D Kolb, C Bader, AM Pobloth, M Griffin, R Nezafat, G Duda, EA Chiocca, JR Stone, JS Michaelson, MN Dean, N Oxman & JC Weaver

3D Printing & Additive Manufacturing 2018

 

Machine Learning + Biomedical Imaging

AI Discovery of TLR Agonist-Driven Phenotypes Reveals Unique Features of Peripheral Cells from Healthy Donors and ART-Suppressed People Living with HIV ↗︎

RW Omange, SC Kim, NS Kolhatkar, T Plott, W Van Trump, K Zhang, H O'Donnell, D Chen, A Hosny, M Wiest, Z Barry, EC Addiego, M Mengistu, P Odorizzi, Y Cai, R Jacobson & JJ Wallin

Frontiers in Immunology 2025

Foundation Model for Cancer Imaging Biomarkers ↗︎

S Pai, D Bontempi, I Hadzic, V Prudente, M Sokač, TL Chaunzwa, S Bernatz, A Hosny, RH Mak, NJ Birkbak & HJWL Aerts

Nature Machine Intelligence 2024

End-to-End Reproducible AI Pipelines in Radiology Using the Cloud ↗︎

D Bontempi, L Nuernberg, S Pai, D Krishnaswamy, V Thiriveedhi, A Hosny, RH Mak, K Farahani, R Kikinis, A Fedorov & HJWL Aerts

Nature Communications 2024

Deep Learning Applications in Lung Cancer Imaging ↗︎↗︎

A Hosny

PhD Maastricht University 2022

Deep Learning-based Detection of Intravenous Contrast in Computed Tomography Scans ↗︎

Z Ye, JM Qian, A Hosny, R Zeleznik, D Plana, J Likitlersuang, Z Zhang, RH Mak, HJWL Aerts & BH Kann

Radiology: Artificial Intelligence 2022

Oral mTOR Inhibition Limits And Reduces Actinic Keratosis And Cutaneous Squamous Cell Carcinoma In A UVB-Induced Mouse Model ↗︎

MG Booty, B Komalo, A Hosny, SE Headland, MT Fernandez-Figueras, AM Nguyen, W Cousin, J Heinrich, L Nicolaisen, RM DeVay, B White & C Elabd

BioRxiv 2022

Artificial Intelligence for Clinical Oncology ↗︎

BH Kann, A Hosny & HJWL Aerts

Cancer Cell 2021

End-to-End Non–Small-Cell Lung Cancer Prognostication Using Deep Learning Applied to Pretreatment Computed Tomography ↗︎

FS Torres, S Akbar, S Raman, K Yasufuku, C Schmidt, A Hosny, F Baldauf-Lenschen & NB Leighl

Journal of Clinical Oncology (JCO) Clinical Cancer Informatics 2021

The Importance of Transparency and Reproducibility in Artificial Intelligence Research ↗︎

B Haibe-Kains, GA Adam, A Hosny, F Khodakarami, MAQC Society Board, L Waldron, B Wang, C McIntosh, A Kundaje, CS Greene, MM Hoffman, JT Leek, W Huber, A Brazma, J Pineau, R Tibshirani, T Hastie, JPA Ioannidis, J Quackenbush & HJWL Aerts​

Nature 2020

Artificial Intelligence in Radiation Oncology ↗︎

E Huynh, A Hosny, C Guthier, D Bitterman, S Petit, DA Haas-Kogan, B Kann, HJWL Aerts & RH Mak

Nature Reviews Clinical Oncology 2020

The Dataset Nutrition Label: A Framework to Drive Higher Data Quality Standards ↗︎ ↗︎

A Hosny*, S Holland*​, S Newman, J Joseph​ & K Chmielinski​

Data Protection and Privacy: Data Protection and Democracy 2020

Deep Learning to Assess Long-term Mortality from Chest Radiographs ↗︎

MT Lu, A Ivanov, T Mayrhofer, A Hosny, HJWL Aerts & U Hoffmann

JAMA Open 2019

Handcrafted Versus Deep Learning Radiomics for Prediction of Cancer Therapy Response ↗︎

A Hosny, HJWL Aerts & RH Mak

The Lancet Digital Health 2019

Artificial Intelligence in Cancer Imaging: Clinical Challenges and Applications ↗︎

WL Bi, A Hosny, MB Schabath, NJ Birkbak, A Mehrtash, ML Giger, T Allison, O Arnaout, C Abbosh, IF Dunn, RH Mak, RM Tamimi, CM Tempany, C Swanton, U Hoffmann, LH Schwartz, RJ Gillies, R Huang & HJWL Aerts

CA: A Cancer Journal for Clinicians 2019

ModelHub.AI: Dissemination Platform for Deep Learning Models ↗︎

A Hosny*, M Schwier*, C Berger, EP Örnek, M Turan, PV Tran, L Weninger, F Isensee, KH Maier-Hein, R McKinley, MT Lu, U Hoffmann, B Menze, S Bakas, A Fedorov & HJWL Aerts

Arxiv Preprint 2019

Data Analysis Strategies in Medical Imaging ↗︎

C Parmar, JD Barry, A Hosny, J Quackenbush & HJWL Aerts

Clinical Cancer Research 2018

Computational Radiomics System to Decode the Radiographic Phenotype ↗︎

JJM van Griethuysen, A Fedorov, C Parmar, A Hosny, N Aucoin, V Narayan, RGH Beets-Tan, JC Fillion-Robin, S Pieper & HJWL Aerts

Cancer Research 2017

 

3D Printing + Biomedical Imaging

Making Data Matter: Voxel Printing for the Digital Fabrication of Data across Scales and Domains ↗︎

C Bader, D Kolb, JC Weaver, S Sharma, A Hosny, J Costa & N Oxman

Science Advances 2018

A Novel Mixed Reality Navigation for Laparoscopic Surgery ↗︎

J Jayender, B Xavier, F King, A Hosny, D Black, S Pieper & A Tavakkoli

Medical Image Computing & Computer Assisted Intervention (MICCAI) 2018

3D Printing and Intraoperative Neuronavigation Tailoring for Skull Base Reconstruction after Extended Endoscopic Endonasal Surgery ↗︎

WI Essayed, P Unadkat, A Hosny, S Frisken, MS Rassi, S Mukundan Jr, JC Weaver, O Al-Mefty, AJ Golby & IF Dunn

Journal of Neurological Surgery 2018

Unlocking Vendor-Specific Tags: Three-Dimensional Printing of Echocardiography Data Sets ↗︎

A Hosny, T Shen, A Kuo, D Long, M Andrawes & JD Dilley

The Journal of Thoracic and Cardiovascular Surgery 2017

Use of a 3D-Printed Abdominal Compression Device to Facilitate CT Fluoroscopy-Guided Percutaneous Interventions ↗︎

Y Epelboym, PB Shyn, A Hosny, T Kelil, JFB Chick, NR Chauhan, B Ripley, RD Nawfel & FJ Scholz

American Journal of Roentgenology 2017

 

Computational Design

Multi-scale Modeling and Mechanical Performance Characterization of Stingray Skeleton-inspired Tessellations ↗︎

AK Jayasankar, R Seidel, A Hosny, JC Weaver, P Fratzl, J Chen & MN Dean

Journal of the Mechanics & Physics of Solids 2020

Hybrid Living Materials: Digital Design and Fabrication of 3D Multimaterial Structures with Programmable Biohybrid Surfaces ↗︎

R Soo Hoo Smith*, C Bader*, S Sharma*, D Kolb, T Tang, A Hosny, F Moser, JC Weaver, CA Voigt & N Oxman

Advanced Functional Materials 2019

Mechanical Behavior of Idealized, Stingray-Skeleton-Inspired Tiled Composites as a Function of Geometry and Material Properties ↗︎

AK Jayasankar, R Seidel, J Naumann, L Guiducci, A Hosny, P Fratzl, JC Weaver, JWC Dunlop & MN Dean

Journal of the Mechanical Behavior of Biomedical Materials 2017

Material Analytics: Knowledge from Mechanical Behaviour Data ↗︎

A Hosny

Master of Design Studies Thesis - Harvard Graduate School of Design 2015

Voxel Beam ↗︎

A Hosny, N Jacobson & Z Seibold

Emerging Experience in Past, Present and Future of Digital Architecture, Proceedings of the 20th International Conference of the Association for Computer-Aided Architectural Design Research in Asia CAADRIA 2015

Robotic Bead Rolling ↗︎

J Friedman, A Hosny & A Lee

Robotic Fabrication in Architecture, Art and Design 2014

 

Editorials About my Work

Cancer Informatics in 2018: The Mysteries of the Cancer Genome Continue to Unravel, Deep Learning Approaches the Clinic, and Passive Data Collection Demonstrates Utility ↗︎

JL Warner & D Patt

International Medical Informatics Association (IMIA) Yearbook of Medical Informatics 2019

Fit-Testing Transcatheter Aortic Valve Replacements with 3-D Printing ↗︎

J Abbasi

The Journal of the American Medical Association (JAMA) 2019

Ultrasound-Derived Three-Dimensional Print Models Made Ultrasimply ↗︎

WJ Mauermann & JM Matsumoto

The Journal of Thoracic and Cardiovascular Surgery 2018

Clinical Validation of Deep Learning Algorithms for Lung Cancer Radiotherapy Targeting ↗︎

A Hosny, DS Bitterman, CV Guthier, JM Qian, H Roberts, S Perni, A Saraf, LC Peng, I Pashtan, Z Ye, BH Kann, DE Kozono, D Christiani, PJ Catalano, HJWL Aerts & RH Mak

Proceedings of the ASTRO Annual Meeting 2021

Deep Learning and Harmonization of Multi-Institutional Data for Automated Gross Tumor and Nodal Segmentation for Oropharyngeal Cancer ↗︎

D Plana, PK Guntaka, JM Qian, P Zhou, A Hosny, DN Margalit, JD Schoenfeld, RB Tishler, RI Haddad, R Uppaluri, B Haibe-Kains, HJWL Aerts & BH Kann

Proceedings of the ASTRO Annual Meeting 2021

Association of a Deep Learning Estimation of Chest Imaging Age With Survival in Patients With Non-Small Cell Lung Cancers Undergoing Radiation ↗︎

S Perni, V Raghu, CV Guthier, J Weiss, E Huynh, A Hosny, E Fite, D Christiani, HJWL Aerts, M Lu & RH Mak

Proceedings of the ASTRO Annual Meeting 2021

Deep Learning Radiomics in Cancer Imaging ↗︎

A Hosny

Clinical Cancer Research 2021

Association of a Deep Learning Estimation of Chest Imaging Age With Survival in Patients With Non-Small Cell Lung Cancers Undergoing Radiation ↗︎

S Perni, V Raghu, CV Guthier, J Weiss, E Huynh, A Hosny, E Fite, D Christiani, H Aerts, M Lu & RH Mak

International Journal of Radiation Oncology, Biology, Physics 2021

Findable, Accessible, Interoperable, Reusable (FAIR) Quantitative Imaging Analysis Workflow ↗︎

Z Shi, A Fedorov, A Hosny, C Parmar, HJWL Aerts, A Dekker & L Wee

European Society for Radiotherapy & Oncology (EESTRO) 2020

FAIR-Radiomics Infrastructure

Z Shi, A Fedorov, A Hosny, C Parmar, HJWL Aerts, A Dekker & L Wee

19th International Conference on the use of Computers in Radiation Therapy (ICCR) 2019

Non-invasive Tracking of Cancer Evolution using Deep Learning Longitudinal Image Analysis ↗︎

Y Xu, A Hosny, T Coroller, R Zeleznik, RH Mak & HJWL Aerts

Radiological Society of North America (RSNA) Scientific Assembly and Annual Meeting 2018

Deep Learning for Automated Quantification of Tumor Phenotypes ↗︎

A Hosny, T Coroller, P Grossmann, C Parmar, R Zeleznik, A Kumar, J Bussink, RJ Gillies, RH Mak & HJWL Aerts

American Association of Physicists in Medicine (AAPM) Annual Meeting 2018

Tracking Imaging Phenotypes with Deep Learning for Survival and Treatment Response Prediction ↗︎

Y Xu, A Hosny, T Coroller, R Zeleznik, RH Mak & HJWL Aerts

American Association of Physicists in Medicine (AAPM) Annual Meeting 2018

Quantitative Shape Analysis of Intertesseral Joints in Tessellated Calcified Cartilage of Sharks and Rays (Elasmobranchs) ↗︎ ↗︎

R Seidel, A Hosny, D Knötel, P Fratzl, D Baum, JC Weaver & MN Dean

5th International Conference on Multifunctional, Hybrid & Nanomaterials 2017

Bricks and Anchors: Strategies for Load Bearing and Muscle Attachment in the Cartilage Skeletons of Sharks and Rays ↗︎

MN Dean, A Hosny, D Knoetel, R Seidel, A Luger, D Wainwright, M Blumer & D Baum

111th Annual Meeting of the German Zoological Society 2017

Biological and Bio-inspired Flexible Armor Based on Chiton’s Girdle Scales ↗︎

L Li, M Connors, A Hosny, D Earnisse, M Dean, JC Weaver & C Ortiz

The Minerals, Metals, and Materials Society (TMS) Annual Meeting & Exhibition 2017

Development, Ultrastructure and Mechanics of Shark and Ray Tessellated Cartilage: Nature’s Curious Alternative to Bone

MN Dean, R Seidel, A Jayasankar, M Blumer, A Hosny, JC Weaver, D Knoetel, D Baum & P Fratzl

Symposium: FishBone - Advancing the Use of Fish for Skeletal Research. European Calcified Tissue Society (ECTS) Meeting 2017

Bricks and Anchors: Strategies for Load Bearing and Muscle Attachment in the Cartilage Skeletons of Sharks and Rays ↗︎

MN Dean, A Hosny, D Knoetel, R Seidel, AM Luger, D Wainwright, M Blumer & D Baum

The Society for Integrative and Comparative Biology (SICB) Annual Meeting 2017

CellExpress: On-Demand Web-Based Cell Microscopy Image Analysis ↗︎

A Hosny, S Pieper & S Baumann

Society of Biomolecular Imaging & Informatics - High Content 3rd Annual Conference 2016

Biological Strategies for Fatigue and Wear Avoidance: Lessons from Stingray Skeletons and Teeth ↗︎

MN Dean, A Hosny, R Seidel & D Baum

3rd International Conference on BioTribology 2016 & Tomography for Scientific Advancement symposium (ToScA) 2016

Understanding the Tiling Rules of the Tessellated Mineralized Endoskeleton of Sharks and Rays ↗︎

D Knötel, R Seidel, A Hosny, JC Weaver, D Baum & MN Dean

Euro Bio-inspired Materials 2016

Mechanical Behavior of Bioinspired Tiled Composites as a Function of Geometry and Material Properties ↗︎

AK Jayasankar, L Guiducci, A Hosny, R Seidel, P Fratzl, J Dunlop, JC Weaver & MN Dean

Euro Bio-inspired Materials 2016

Three-Dimensional Printing of an Abdominal Compression Device to Facilitate CT-Fluoroscopy-Guided Interventional Procedures ↗︎

Y Epelboym, P Shyn, T Kelil, J Chick, N Chauhan, B Ripley, A Hosny & F Scholz

Journal of Vascular and Interventional Radiology 2015

Nature’s Puncture Resistant Flexible Composites: Design Lessons from Shark Skeletons

R Seidel, AM Luger, D Knoetel, M Schotte, D Baum, M Blumer, L Li, A Hosny, JC Weaver & MN Dean

HFSP Annual Awardees Meeting 2015

Robotic Bead Rolling ↗︎

J Friedman, A Hosny & A Lee

Projects of the 34th ACADIA Annual Conference 2014

Deep Learning Applications in Lung Cancer Imaging

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PhD Defense
Maastricht University. April 6 2022

Deep Learning Radiomics in Cancer Imaging

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Plenary Session 2: Learning from Images: Radiomics
AACR Virtual Special Conference on Artificial Intelligence, Diagnosis, and Imaging. Philadelphia, 13-14 Jan 2021

Artificial Intelligence in Radiation Oncology

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Research Showcase, Department of Radiation Oncology
Brigham and Women's Hospital/Dana Farber Cancer Institute. Boston, 27 June 2019

Artificial Intelligence in Radiology

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Global Health Catalyst Speaker Series. March 17 2019

Artificial Intelligence in Radiology

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Physics Seminar, Department of Radiation Oncology
Massachusetts General Hospital. Boston, 9 October 2018

Convolutional Neural Networks

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Certificate Series Session 3: Convolutional Neural Networks
Self Assessment Modules (SAM) Joint Imaging-Therapy Scientific Symposium
American Association of Physicists in Medicine (AAPM) Annual Meeting. Nashville, 1 August 2018

Deep Learning Intuition

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Certificate Series Session 2: Machine Learning for Radiomics
Self Assessment Modules (SAM) Joint Imaging-Therapy Scientific Symposium
American Association of Physicists in Medicine (AAPM) Annual Meeting. Nashville, 1 August 2018

Deep Learning for Automated Quantification of Tumor Phenotypes

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Computed Tomography II - Imaging Scientific Session
American Association of Physicists in Medicine (AAPM) Annual Meeting. Nashville, 1 August 2018

Modelhub: Plug & Predict Solutions for Reproducible AI Research

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National Cancer Institute (NCI) Containers and Workflows Interest Group Seminar. Boston, 13 July 2018

Deep Learning Opportunities in Cancer Imaging

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ReWork Deep Learning in Healthcare Summit. Boston, 24-25 May 2018

From physical to digital and back: How 3D modeling and additive manufacturing reveal nature's design rules

International Congress of Vertebrate Morphology. Washington DC, 29 June – 3 July 2016

Methods and Systems for Determining Health of an Organ Based on Medical Image Data Using Artificial Intelligence ↗︎

A Hosny & HJ Aerts

U.S. Patent No. 12,183,468, Application No. 18824547, filed December 31, 2024

Methodology and Aparatus for Simulation of Medical Devices ↗︎

A Hosny, B Ripley, T Kelil, J Dilley & J Weaver

International Application No. PCT/US2017/060523, filed August 11, 2017
U.S. Provisional Pat. Ser. No. 62/419268, filed November 8, 2016

Flexible Scaled Protective Systems

L Li, A Hosny, M Connors & C Ortiz

U.S. Provisional Pat. Ser. No. 62/357580, filed July 1, 2016