Highlights
Clinical Validation of Deep Learning Algorithms for Lung Cancer Radiotherapy Targeting ↗︎
A Hosny, DS Bitterman, CV Guthier, JM Qian, H Roberts, S Perni, A Saraf, LC Peng, I Pashtan, Z Ye, BH Kann, DE Kozono, D Christiani, PJ Catalano, HJWL Aerts & RH Mak
The Lancet Digital Health 2022
Deep Learning-based Computed Tomography Radiomics for Non-small Cell Lung Cancer Histopathologic Classification ↗︎
TL Chaunzwa, A Hosny, Y Xu, A Shafer, N Diao, M Lanuti, DC Christiani, RH Mak & HJWL Aerts
Nature Scientific Reports 2021
Artificial Intelligence for Global Health ↗︎
A Hosny & HJWL Aerts
Science 2019
Deep Learning Predicts Lung Cancer Treatment Response from Serial Medical Imaging ↗︎
Y Xu, A Hosny, R Zeleznik, C Parmar, T Coroller, I Franko, RH Mak & HJWL Aerts
Clinical Cancer Research 2019
Bioinspired Design of Flexible Armor Based on Chiton Scales ↗︎
M Connors*, T Yang*, A Hosny, Z Deng, F Yazdandoost, H Massaadi, D Eernisse, R Mirzaeifar, MN Dean, JC Weaver, C Ortiz & L Li
Nature Communications 2019
Artificial Intelligence in Radiology ↗︎
A Hosny, C Parmar, J Quackenbush, LZ Schwartz & HJWL Aerts
Nature Reviews Cancer 2018
Deep Learning for Lung Cancer Prognostication: A Retrospective Multi-Cohort Radiomics Study ↗︎
A Hosny, C Parmar, T Coroller, P Grossmann, R Zeleznik, A Kumar, J Bussink, RJ Gillies, RH Mak & HJWL Aerts
PLOS Medicine 2018
Pre-procedural Fit-testing of Transcatheter Aortic Valve Replacement (TAVR) Valves Using Parametric Modeling and 3D Printing ↗︎
A Hosny, J Dilley, T Kelil, M Mathur, M Dean, JC Weaver & B Ripley
Journal of Cardiovascular Computed Tomography 2018
From Improved Diagnostics to Presurgical Planning: High Resolution Functionally Graded Multi-material 3D Printing of Biomedical Tomographic Datasets ↗︎
A Hosny, S Keating, JD Dilley, B Ripley, T Kelil, S Pieper, D Kolb, C Bader, AM Pobloth, M Griffin, R Nezafat, G Duda, EA Chiocca, JR Stone, JS Michaelson, MN Dean, N Oxman & JC Weaver
3D Printing & Additive Manufacturing 2018
Machine Learning + Biomedical Imaging
AI Discovery of TLR Agonist-Driven Phenotypes Reveals Unique Features of Peripheral Cells from Healthy Donors and ART-Suppressed People Living with HIV ↗︎
RW Omange, SC Kim, NS Kolhatkar, T Plott, W Van Trump, K Zhang, H O'Donnell, D Chen, A Hosny, M Wiest, Z Barry, EC Addiego, M Mengistu, P Odorizzi, Y Cai, R Jacobson & JJ Wallin
Frontiers in Immunology 2025
Foundation Model for Cancer Imaging Biomarkers ↗︎
S Pai, D Bontempi, I Hadzic, V Prudente, M Sokač, TL Chaunzwa, S Bernatz, A Hosny, RH Mak, NJ Birkbak & HJWL Aerts
Nature Machine Intelligence 2024
End-to-End Reproducible AI Pipelines in Radiology Using the Cloud ↗︎
D Bontempi, L Nuernberg, S Pai, D Krishnaswamy, V Thiriveedhi, A Hosny, RH Mak, K Farahani, R Kikinis, A Fedorov & HJWL Aerts
Nature Communications 2024
Deep Learning Applications in Lung Cancer Imaging ↗︎↗︎
A Hosny
PhD Maastricht University 2022
Deep Learning-based Detection of Intravenous Contrast in Computed Tomography Scans ↗︎
Z Ye, JM Qian, A Hosny, R Zeleznik, D Plana, J Likitlersuang, Z Zhang, RH Mak, HJWL Aerts & BH Kann
Radiology: Artificial Intelligence 2022
Oral mTOR Inhibition Limits And Reduces Actinic Keratosis And Cutaneous Squamous Cell Carcinoma In A UVB-Induced Mouse Model ↗︎
MG Booty, B Komalo, A Hosny, SE Headland, MT Fernandez-Figueras, AM Nguyen, W Cousin, J Heinrich, L Nicolaisen, RM DeVay, B White & C Elabd
BioRxiv 2022
Artificial Intelligence for Clinical Oncology ↗︎
BH Kann, A Hosny & HJWL Aerts
Cancer Cell 2021
End-to-End Non–Small-Cell Lung Cancer Prognostication Using Deep Learning Applied to Pretreatment Computed Tomography ↗︎
FS Torres, S Akbar, S Raman, K Yasufuku, C Schmidt, A Hosny, F Baldauf-Lenschen & NB Leighl
Journal of Clinical Oncology (JCO) Clinical Cancer Informatics 2021
The Importance of Transparency and Reproducibility in Artificial Intelligence Research ↗︎
B Haibe-Kains, GA Adam, A Hosny, F Khodakarami, MAQC Society Board, L Waldron, B Wang, C McIntosh, A Kundaje, CS Greene, MM Hoffman, JT Leek, W Huber, A Brazma, J Pineau, R Tibshirani, T Hastie, JPA Ioannidis, J Quackenbush & HJWL Aerts
Nature 2020
Artificial Intelligence in Radiation Oncology ↗︎
E Huynh, A Hosny, C Guthier, D Bitterman, S Petit, DA Haas-Kogan, B Kann, HJWL Aerts & RH Mak
Nature Reviews Clinical Oncology 2020
The Dataset Nutrition Label: A Framework to Drive Higher Data Quality Standards ↗︎ ↗︎
A Hosny*, S Holland*, S Newman, J Joseph & K Chmielinski
Data Protection and Privacy: Data Protection and Democracy 2020
Deep Learning to Assess Long-term Mortality from Chest Radiographs ↗︎
MT Lu, A Ivanov, T Mayrhofer, A Hosny, HJWL Aerts & U Hoffmann
JAMA Open 2019
Handcrafted Versus Deep Learning Radiomics for Prediction of Cancer Therapy Response ↗︎
A Hosny, HJWL Aerts & RH Mak
The Lancet Digital Health 2019
Artificial Intelligence in Cancer Imaging: Clinical Challenges and Applications ↗︎
WL Bi, A Hosny, MB Schabath, NJ Birkbak, A Mehrtash, ML Giger, T Allison, O Arnaout, C Abbosh, IF Dunn, RH Mak, RM Tamimi, CM Tempany, C Swanton, U Hoffmann, LH Schwartz, RJ Gillies, R Huang & HJWL Aerts
CA: A Cancer Journal for Clinicians 2019
ModelHub.AI: Dissemination Platform for Deep Learning Models ↗︎
A Hosny*, M Schwier*, C Berger, EP Örnek, M Turan, PV Tran, L Weninger, F Isensee, KH Maier-Hein, R McKinley, MT Lu, U Hoffmann, B Menze, S Bakas, A Fedorov & HJWL Aerts
Arxiv Preprint 2019
Data Analysis Strategies in Medical Imaging ↗︎
C Parmar, JD Barry, A Hosny, J Quackenbush & HJWL Aerts
Clinical Cancer Research 2018
Computational Radiomics System to Decode the Radiographic Phenotype ↗︎
JJM van Griethuysen, A Fedorov, C Parmar, A Hosny, N Aucoin, V Narayan, RGH Beets-Tan, JC Fillion-Robin, S Pieper & HJWL Aerts
Cancer Research 2017
3D Printing + Biomedical Imaging
Making Data Matter: Voxel Printing for the Digital Fabrication of Data across Scales and Domains ↗︎
C Bader, D Kolb, JC Weaver, S Sharma, A Hosny, J Costa & N Oxman
Science Advances 2018
A Novel Mixed Reality Navigation for Laparoscopic Surgery ↗︎
J Jayender, B Xavier, F King, A Hosny, D Black, S Pieper & A Tavakkoli
Medical Image Computing & Computer Assisted Intervention (MICCAI) 2018
3D Printing and Intraoperative Neuronavigation Tailoring for Skull Base Reconstruction after Extended Endoscopic Endonasal Surgery ↗︎
WI Essayed, P Unadkat, A Hosny, S Frisken, MS Rassi, S Mukundan Jr, JC Weaver, O Al-Mefty, AJ Golby & IF Dunn
Journal of Neurological Surgery 2018
Unlocking Vendor-Specific Tags: Three-Dimensional Printing of Echocardiography Data Sets ↗︎
A Hosny, T Shen, A Kuo, D Long, M Andrawes & JD Dilley
The Journal of Thoracic and Cardiovascular Surgery 2017
Use of a 3D-Printed Abdominal Compression Device to Facilitate CT Fluoroscopy-Guided Percutaneous Interventions ↗︎
Y Epelboym, PB Shyn, A Hosny, T Kelil, JFB Chick, NR Chauhan, B Ripley, RD Nawfel & FJ Scholz
American Journal of Roentgenology 2017
Computational Design
Multi-scale Modeling and Mechanical Performance Characterization of Stingray Skeleton-inspired Tessellations ↗︎
AK Jayasankar, R Seidel, A Hosny, JC Weaver, P Fratzl, J Chen & MN Dean
Journal of the Mechanics & Physics of Solids 2020
Hybrid Living Materials: Digital Design and Fabrication of 3D Multimaterial Structures with Programmable Biohybrid Surfaces ↗︎
R Soo Hoo Smith*, C Bader*, S Sharma*, D Kolb, T Tang, A Hosny, F Moser, JC Weaver, CA Voigt & N Oxman
Advanced Functional Materials 2019
Mechanical Behavior of Idealized, Stingray-Skeleton-Inspired Tiled Composites as a Function of Geometry and Material Properties ↗︎
AK Jayasankar, R Seidel, J Naumann, L Guiducci, A Hosny, P Fratzl, JC Weaver, JWC Dunlop & MN Dean
Journal of the Mechanical Behavior of Biomedical Materials 2017
Material Analytics: Knowledge from Mechanical Behaviour Data ↗︎
A Hosny
Master of Design Studies Thesis - Harvard Graduate School of Design 2015
Voxel Beam ↗︎
A Hosny, N Jacobson & Z Seibold
Emerging Experience in Past, Present and Future of Digital Architecture, Proceedings of the 20th International Conference of the Association for Computer-Aided Architectural Design Research in Asia CAADRIA 2015
Robotic Bead Rolling ↗︎
J Friedman, A Hosny & A Lee
Robotic Fabrication in Architecture, Art and Design 2014
Editorials About my Work
Cancer Informatics in 2018: The Mysteries of the Cancer Genome Continue to Unravel, Deep Learning Approaches the Clinic, and Passive Data Collection Demonstrates Utility ↗︎
JL Warner & D Patt
International Medical Informatics Association (IMIA) Yearbook of Medical Informatics 2019
Fit-Testing Transcatheter Aortic Valve Replacements with 3-D Printing ↗︎
J Abbasi
The Journal of the American Medical Association (JAMA) 2019
Ultrasound-Derived Three-Dimensional Print Models Made Ultrasimply ↗︎
WJ Mauermann & JM Matsumoto
The Journal of Thoracic and Cardiovascular Surgery 2018
Clinical Validation of Deep Learning Algorithms for Lung Cancer Radiotherapy Targeting ↗︎
A Hosny, DS Bitterman, CV Guthier, JM Qian, H Roberts, S Perni, A Saraf, LC Peng, I Pashtan, Z Ye, BH Kann, DE Kozono, D Christiani, PJ Catalano, HJWL Aerts & RH Mak
Proceedings of the ASTRO Annual Meeting 2021
Deep Learning and Harmonization of Multi-Institutional Data for Automated Gross Tumor and Nodal Segmentation for Oropharyngeal Cancer ↗︎
D Plana, PK Guntaka, JM Qian, P Zhou, A Hosny, DN Margalit, JD Schoenfeld, RB Tishler, RI Haddad, R Uppaluri, B Haibe-Kains, HJWL Aerts & BH Kann
Proceedings of the ASTRO Annual Meeting 2021
Association of a Deep Learning Estimation of Chest Imaging Age With Survival in Patients With Non-Small Cell Lung Cancers Undergoing Radiation ↗︎
S Perni, V Raghu, CV Guthier, J Weiss, E Huynh, A Hosny, E Fite, D Christiani, HJWL Aerts, M Lu & RH Mak
Proceedings of the ASTRO Annual Meeting 2021
Deep Learning Radiomics in Cancer Imaging ↗︎
A Hosny
Clinical Cancer Research 2021
Association of a Deep Learning Estimation of Chest Imaging Age With Survival in Patients With Non-Small Cell Lung Cancers Undergoing Radiation ↗︎
S Perni, V Raghu, CV Guthier, J Weiss, E Huynh, A Hosny, E Fite, D Christiani, H Aerts, M Lu & RH Mak
International Journal of Radiation Oncology, Biology, Physics 2021
Findable, Accessible, Interoperable, Reusable (FAIR) Quantitative Imaging Analysis Workflow ↗︎
Z Shi, A Fedorov, A Hosny, C Parmar, HJWL Aerts, A Dekker & L Wee
European Society for Radiotherapy & Oncology (EESTRO) 2020
FAIR-Radiomics Infrastructure
Z Shi, A Fedorov, A Hosny, C Parmar, HJWL Aerts, A Dekker & L Wee
19th International Conference on the use of Computers in Radiation Therapy (ICCR) 2019
Non-invasive Tracking of Cancer Evolution using Deep Learning Longitudinal Image Analysis ↗︎
Y Xu, A Hosny, T Coroller, R Zeleznik, RH Mak & HJWL Aerts
Radiological Society of North America (RSNA) Scientific Assembly and Annual Meeting 2018
Deep Learning for Automated Quantification of Tumor Phenotypes ↗︎
A Hosny, T Coroller, P Grossmann, C Parmar, R Zeleznik, A Kumar, J Bussink, RJ Gillies, RH Mak & HJWL Aerts
American Association of Physicists in Medicine (AAPM) Annual Meeting 2018
Tracking Imaging Phenotypes with Deep Learning for Survival and Treatment Response Prediction ↗︎
Y Xu, A Hosny, T Coroller, R Zeleznik, RH Mak & HJWL Aerts
American Association of Physicists in Medicine (AAPM) Annual Meeting 2018
Quantitative Shape Analysis of Intertesseral Joints in Tessellated Calcified Cartilage of Sharks and Rays (Elasmobranchs) ↗︎ ↗︎
R Seidel, A Hosny, D Knötel, P Fratzl, D Baum, JC Weaver & MN Dean
5th International Conference on Multifunctional, Hybrid & Nanomaterials 2017
Bricks and Anchors: Strategies for Load Bearing and Muscle Attachment in the Cartilage Skeletons of Sharks and Rays ↗︎
MN Dean, A Hosny, D Knoetel, R Seidel, A Luger, D Wainwright, M Blumer & D Baum
111th Annual Meeting of the German Zoological Society 2017
Biological and Bio-inspired Flexible Armor Based on Chiton’s Girdle Scales ↗︎
L Li, M Connors, A Hosny, D Earnisse, M Dean, JC Weaver & C Ortiz
The Minerals, Metals, and Materials Society (TMS) Annual Meeting & Exhibition 2017
Development, Ultrastructure and Mechanics of Shark and Ray Tessellated Cartilage: Nature’s Curious Alternative to Bone
MN Dean, R Seidel, A Jayasankar, M Blumer, A Hosny, JC Weaver, D Knoetel, D Baum & P Fratzl
Symposium: FishBone - Advancing the Use of Fish for Skeletal Research. European Calcified Tissue Society (ECTS) Meeting 2017
Bricks and Anchors: Strategies for Load Bearing and Muscle Attachment in the Cartilage Skeletons of Sharks and Rays ↗︎
MN Dean, A Hosny, D Knoetel, R Seidel, AM Luger, D Wainwright, M Blumer & D Baum
The Society for Integrative and Comparative Biology (SICB) Annual Meeting 2017
CellExpress: On-Demand Web-Based Cell Microscopy Image Analysis ↗︎
A Hosny, S Pieper & S Baumann
Society of Biomolecular Imaging & Informatics - High Content 3rd Annual Conference 2016
Biological Strategies for Fatigue and Wear Avoidance: Lessons from Stingray Skeletons and Teeth ↗︎
MN Dean, A Hosny, R Seidel & D Baum
3rd International Conference on BioTribology 2016 & Tomography for Scientific Advancement symposium (ToScA) 2016
Understanding the Tiling Rules of the Tessellated Mineralized Endoskeleton of Sharks and Rays ↗︎
D Knötel, R Seidel, A Hosny, JC Weaver, D Baum & MN Dean
Euro Bio-inspired Materials 2016
Mechanical Behavior of Bioinspired Tiled Composites as a Function of Geometry and Material Properties ↗︎
AK Jayasankar, L Guiducci, A Hosny, R Seidel, P Fratzl, J Dunlop, JC Weaver & MN Dean
Euro Bio-inspired Materials 2016
Three-Dimensional Printing of an Abdominal Compression Device to Facilitate CT-Fluoroscopy-Guided Interventional Procedures ↗︎
Y Epelboym, P Shyn, T Kelil, J Chick, N Chauhan, B Ripley, A Hosny & F Scholz
Journal of Vascular and Interventional Radiology 2015
Nature’s Puncture Resistant Flexible Composites: Design Lessons from Shark Skeletons
R Seidel, AM Luger, D Knoetel, M Schotte, D Baum, M Blumer, L Li, A Hosny, JC Weaver & MN Dean
HFSP Annual Awardees Meeting 2015
Robotic Bead Rolling ↗︎
J Friedman, A Hosny & A Lee
Projects of the 34th ACADIA Annual Conference 2014
Deep Learning Applications in Lung Cancer Imaging
video↗︎
PhD Defense
Maastricht University. April 6 2022
Deep Learning Radiomics in Cancer Imaging
slides↗︎ video↗︎
Plenary Session 2: Learning from Images: Radiomics
AACR Virtual Special Conference on Artificial Intelligence, Diagnosis, and Imaging. Philadelphia, 13-14 Jan 2021
Artificial Intelligence in Radiation Oncology
slides↗︎
Research Showcase, Department of Radiation Oncology
Brigham and Women's Hospital/Dana Farber Cancer Institute. Boston, 27 June 2019
Artificial Intelligence in Radiology
video↗︎
Global Health Catalyst Speaker Series. March 17 2019
Artificial Intelligence in Radiology
slides↗︎
Physics Seminar, Department of Radiation Oncology
Massachusetts General Hospital. Boston, 9 October 2018
Convolutional Neural Networks
page↗︎
slides↗︎
video↗︎
Certificate Series Session 3: Convolutional Neural Networks
Self Assessment Modules (SAM) Joint Imaging-Therapy Scientific Symposium
American Association of Physicists in Medicine (AAPM) Annual Meeting. Nashville, 1 August 2018
Deep Learning Intuition
page↗︎
slides↗︎
video↗︎
Certificate Series Session 2: Machine Learning for Radiomics
Self Assessment Modules (SAM) Joint Imaging-Therapy Scientific Symposium
American Association of Physicists in Medicine (AAPM) Annual Meeting. Nashville, 1 August 2018
Deep Learning for Automated Quantification of Tumor Phenotypes
page↗︎
slides↗︎
Computed Tomography II - Imaging Scientific Session
American Association of Physicists in Medicine (AAPM) Annual Meeting. Nashville, 1 August 2018
Modelhub: Plug & Predict Solutions for Reproducible AI Research
slides↗︎
National Cancer Institute (NCI) Containers and Workflows Interest Group Seminar. Boston, 13 July 2018
Deep Learning Opportunities in Cancer Imaging
slides↗︎
video↗︎
ReWork Deep Learning in Healthcare Summit. Boston, 24-25 May 2018
From physical to digital and back: How 3D modeling and additive manufacturing reveal nature's design rules
International Congress of Vertebrate Morphology. Washington DC, 29 June – 3 July 2016
CA: A Cancer Journal for Clinicians
Journal of Cardiovascular Computed Tomography
Nature Reviews Cancer
Science Advances
Small
Methods and Systems for Determining Health of an Organ Based on Medical Image Data Using Artificial Intelligence ↗︎
A Hosny & HJ Aerts
U.S. Patent No. 12,183,468, Application No. 18824547, filed December 31, 2024
Methodology and Aparatus for Simulation of Medical Devices ↗︎
A Hosny, B Ripley, T Kelil, J Dilley & J Weaver
International Application No. PCT/US2017/060523, filed August 11, 2017
U.S. Provisional Pat. Ser. No. 62/419268, filed November 8, 2016
Flexible Scaled Protective Systems
L Li, A Hosny, M Connors & C Ortiz
U.S. Provisional Pat. Ser. No. 62/357580, filed July 1, 2016